Synvisc, NeoVisc, Orthovisc viscosupplementation injections
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NeoVisc is a 1.0% solution of highly purified Sodium Hyaluronate. Hyaluronate is a naturally occurring polysaccharide found in connective tissue, synovial fluid, vitreous humor of the eye, birth canal etc. It has been shown to play an important role in many biological processes such as embryonic development, cell differentiation, tissue hydration and proteoglycan organization.

Patients with OA typically experience pain and loss of mobility because of changes to the internal environment of the affected joint. NeoVisc works as a viscosupplement by improving the natural viscosity and elasticity of synovial fluid, thereby increasing lubrication, joint mobility and decreasing pain.

Viscosupplement treatments are not appropriate for all osteoarthritis patients. Discuss NeoVisc with your doctor to see if you are a candidate for viscosupplement therapy.

We are not aware of any significant differences in treatment outcome with any of the hyaluronate products presently being used in Canada however, NeoVisc can cost up to 50% less than other hyaluronate products. For more information on NeoVisc visit: www.stellarint.com

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ORTHOVISC is a sterile, non-pyrogenic solution of sodium hyaluronate.

Sodium hyaluronate is a high molecular weight polysaccharide composed of sodium glucuronate and N-acetylglucosamine. Sodium hyaluronate is ubiquitously distributed throughout the tissues of the body and is present in high concentrations in such tissues as vitreous humor, synovial fluid, umbilical cord and dermis. Sodium hyaluronate functions as a tissue lubricant and is thought to play an important role in modulating the physical and mechanical interactions between adjacent tissues. It can also act as a visco-elastic support maintaining a separation between tissues.  ORTHOVISC is non-inflammatory, is non-pyrogenic and is well tolerated. Sodium hyaluronate preparation has been shown to be non-antigenic. ORTHOVISC does not interfere with normal wound healing processes.

ORTHOVISC is indicated for the symptomatic treatment of temporomandibular joint dysfunction and osteoarthritis of the knee.

At the present time there are no known contraindications to the use of ORTHOVISC when used in the symptomatic treatment of the joint disease.

Individuals prone to chicken-or chicken-derived product allergies could, conceivably, experience an adverse reaction to sodium hyaluronate preparations. However, such reactions have not been reported previously, despite wide usage of sodium hyaluronate in the form of preparations identical to ORTHOVISC during other surgical procedures. There are minimal risks associated with the procedure of injecting substances into joints in general; primarily infection and bleeding. Pre-existing infections of skin in the region of the intended injection or known systemic bleeding disorders may constitute relative or absolute contraindications.

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